
Why "Normal" Lab Results Don't Mean Optimal Health
Why 'Normal' Lab Results Don’t Mean Optimal Health
Have you ever been told that your lab results are "normal," but you still feel tired, foggy, or just not yourself? Here’s the truth—"normal" lab results don’t always mean optimal health. Today, we’ll dive into the difference between "normal" and "optimal" levels and why it matters for your brain and overall health.
What Does "Normal" Really Mean?
Let’s clarify what "normal" means when it comes to lab tests. "Normal" lab ranges are often based on averages from the general population, which includes people with a range of health issues. The lab is essentially saying, "This level is common in the population," not necessarily that it’s ideal for health. This means you could be within the "normal" range but still not feel your best or have underlying health issues.
Why the Difference Matters for Brain Health
Optimal ranges, on the other hand, are based on what’s ideal for optimal function and long-term health. While "normal" means you’re statistically in the average, "optimal" aims for the best function, especially for sensitive organs like the brain. For example, markers like homocysteine, vitamin D, and CRP (C-reactive protein) can show what’s really going on with brain health and inflammation. These are markers where the difference between "normal" and "optimal" can be significant.
Example 1: Methylation and Homocysteine Levels
Methylation is a process that’s crucial for brain health, as it affects neurotransmitter production, detoxification, and DNA repair. One marker that often reflects methylation health is homocysteine. The "normal" range for homocysteine might go up to 15 µmol/L, but optimal health experts suggest levels closer to 7 µmol/L or lower. Higher homocysteine levels can indicate methylation issues, often tied to genetics like MTHFR variations, and can contribute to neuroinflammation, brain fog, and even an increased risk of cognitive decline. So, even if your homocysteine is considered "normal," if it’s above that optimal range, it could be impacting your brain.
Example 2: Leaky Gut Markers – Albumin, Globulin, and Total Protein
Leaky gut, or intestinal permeability, doesn’t just impact digestion; it can affect brain health by allowing toxins to enter the bloodstream and reach the brain. In routine bloodwork, albumin, globulin, and total protein levels can provide insights into gut health.
For instance, albumin and globulin are proteins that help maintain the integrity of the gut lining. When levels are out of optimal range, it can indicate inflammation or permeability in the gut. Low total protein or imbalances in the albumin-to-globulin ratio can be early signs of compromised gut integrity. When the gut lining weakens, toxins and undigested food particles can leak into the bloodstream, leading to systemic inflammation, which in turn may cause brain fog, mood swings, and memory issues.
Example 3: Inflammatory Markers – CRP and Omega-3 Index
Inflammation is a key factor in brain health, and two markers to watch for are CRP (C-reactive protein) and the Omega-3 index. CRP is a general marker of inflammation, and while levels up to 3 mg/L are often considered "normal," optimal levels should ideally be under 1 mg/L for brain health. Chronic low-grade inflammation, even within the "normal" range, can contribute to conditions like brain fog and depression.
The Omega-3 index measures the amount of Omega-3 fatty acids in your blood, which are essential for brain function and reducing inflammation. While there may be no official "normal" range for this marker, optimal levels are considered above 8%. Lower levels can indicate insufficient anti-inflammatory support for the brain, leading to cognitive issues over time.
Why Understanding Optimal Health Is Empowering
Knowing the difference between "normal" and "optimal" can empower you to take control of your health. Just because you’re in the "normal" range doesn’t mean you’re set up for long-term health. Looking at markers from an optimal perspective can help you address issues early on, before they turn into serious health problems.
How to Work Toward Optimal Health: Steps to Take
If you’re looking to achieve optimal health, start by working with a health professional who understands functional or integrative medicine. They can help interpret your lab results from an optimal health perspective and provide guidance on lifestyle changes, diet, and supplements to help you reach those levels. Simple changes like reducing sugar intake, increasing Omega-3-rich foods, and managing stress can make a significant difference.
Understand Your Bloodwork

If you already have bloodwork and would like to understand it through a functional lens, then click here to allow me to provide you with an analysis. If you need to get bloodwork done, let me know so that I can either tell you which tests to request from your doctor, or request them for you if you don't have insurance that covers it.
Final Thoughts
"Normal" lab results don’t always mean you’re thriving. Strive for optimal health and listen to your body. By understanding your lab results through the lens of what’s optimal, not just what’s average, you can take proactive steps to enhance your health and well-being.
If this article was helpful, please consider sharing it with someone who might need to hear this message. Together, we can encourage a mindset shift from accepting "normal" to striving for optimal health.
Healing starts at the cell - Download my free Cell Health Checklist
Healing starts at the cell. If you are curious about the health status of your cell and whether or not you may be experiencing inflammation, click here for my free Cell Health Checklist.